1.
Progressive alcohol-related liver fibrosis is characterised by imbalanced collagen formation and degradation.
Thiele M, Johansen S, Gudmann NS, Madsen B, Kjaergaard M, Nielsen MJ, Leeming DJ, Jacobsen S, Bendtsen F, Møller S, Detlefsen S, Karsdal M, Krag A, GALAXY consortium ,
Arumugam M,
Bork P, Hansen T, Anastasiadou E, Hartoft C, Israelsen H, Legido-Quigley C, Melberg HO, Trebicka J
Liver fibrosis accumulation is considered a turnover disease, with formation exceeding degradation, although this hypothesis has never been tested in humans.