Spatiotemporal variation of mammalian protein complex stoichiometries.
Ori A, Iskar M
, Buczak K, Kastritis P, Parca L
, Andrés-Pons A, Singer S, Bork P
, Beck M
2016 Mar 14; 17(1): 47. Epub 2016 Mar 14; PubMed: 26975353.
Abstract + PDF
Recent large-scale studies revealed cell-type specific proteomes. However, protein complexes, the basic functional modules of a cell, have been so far mostly considered as static entities with well-defined structures. The co-expression of their members has not been systematically charted at the protein level.